David Saire was thought suitable for both Dr. Kuhn and Brouhandier.

Heather Chasen was a contender for the role of Magda.

Montgomery Clift had so many health problems on the set of this film, that Universal sued him for the cost of the film's production delays. During the trial, the film opened and was such a huge hit that Clift's lawyers brought up the point that the film was doing well because of Clift's involvement. Clift won a lucrative settlement.

Jean-Paul Sartre wrote the original script at the request of director John Huston, but it was unused as it was too long. It was later published in book form as "The Freud Scenario."

Robert LaGuardia, in his 1988 biography of Montgomery Clift "Monty," claimed that director John Huston, who had paternalistic feelings towards Clift after directing the alcoholic and emotionally troubled actor in The Misfits, became sadistic towards him during the troubled "Freud" shoot. Basing his charges on interviews with co-star Susannah York, LaGuardia claimed that Huston kept asking Clift about the Freudian concept of "represssion," obviously alluding to Clift's repressed homosexuality. Apparently, Huston himself could not broach the idea that Monty was gay in his own mind, but subconsciously, he reacted to Monty's homosexuality quite negatively. (Marilyn Monroe had admonished Monty not to work with Huston again, finding him a sadist on the "Misfits" set. Her ex-husband Arthur Miller, on the other hand, did not fault Huston in his autobiography "Timebends," but instead, marveled about how he kept his cool during the "Misfits" shoot, which was also troubled due to Marilyn Monroe's mental illness and frequent absences from the set.) Monty's biographer thought that Huston still had paternalistic feelings towards the actor, but was subco